Cardioprotective Brain Mechanisms

Cardioprotective brain mechanisms.

Genome reprogramming by triggering cardioprotective mechanisms

With increasing life expectancy an ever increasing number of elderly patients will be undergoing cardiovascular and non-cardiovascular surgery. These elderly patients may suffer from cardiovascular diseases or may carry cardiovascular risk factors, which both contribute to an increased risk of perioperative complications including cardiac infarction and cardiac death. The ether-derived halogena...

Cisplatin-induced cardiotoxicity: Mechanisms and cardioprotective strategies.

Increased oxidative stress and apoptosis have been implicated in the cardiotoxicity that limits the clinical use of cisplatin as an anti-tumoral drug. Our study was conducted to evaluate the protective potential of acetyl-l-carnitine, DL-α-lipoic acid and silymarin against cisplatin-induced myocardial injury. Eighty male albino rats were divided into eight groups. The first four groups were tre...

Emerging mechanisms for secondary cardioprotective effects of statins.

See article by Li et al. [11] (pages 130 –135) in this observations noting these secondary statin effects were issue. correct; however, the mechanisms responsible have only recently begun to come to light. In this issue of Cardiovascular Research, Li et al. [11] demonstrate that

Cancer Therapy–Induced Cardiotoxicity: Basic Mechanisms and Potential Cardioprotective Therapies

Case Presentation T he patient is a 63-year-old man with a history of wellcontrolled hypertension who is diagnosed with diffuse large B-cell lymphoma and treated with a doxorubicincontaining chemotherapy regimen. During therapy, he is continued on hydrochlorothiazide for his hypertension. Three months later, he complains of dyspnea on exertion and mild lower extremity edema. A transthoracic ech...